Steven Yeun

Mark Grayson / Invincible (voice)

Sandra Oh

Debbie Grayson (voice)

Gillian Jacobs

Samantha Eve Wilkins / Atom Eve (voice)

J.K. Simmons

Nolan Grayson / Omni-Man (voice)

Zachary Quinto

Robot (voice)

Zazie Beetz

Amber Bennett (voice)

Jason Mantzoukas

Rex Sloan / Rex Splode (voice)

Grey DeLisle

Monster Girl/ Shrinking Rae/ Amanda/ Olga/ Thula/ Betsy (voice)

Walton Goggins

Cecil Stedman (voice)

Andrew Rannells

William Clockwell (voice)

Kevin Michael Richardson

Mauler Twins/ King Mauler/ Monster Girl's Monster Form (voice)

Melise

Kate Cha / Dupli-Kate (voice)

Khary Payton

Black Samson

Chris Diamantopoulos

Donald Ferguson

Mark Hamill

Art Rosebaum

Ross Marquand

The Immortal

Clancy Brown

Damien Darkblood

Fred Tatasciore

Eve's Father